Bensedin® 10mg/2mL je lek koji sadrži aktivnu supstancu 'diazepam' i koristi se za olakšanje simptoma teške anksioznosti, relaksaciju mišića i lečenje epilepsije kod odraslih, kao i za smanjenje napetosti kod dece sa cerebralnom spastičnošću.
Postoje naznake da, u slučaju benzodiazepina kratkog dejstva, simptomi obustave mogu da se manifestuju unutar doznog intervala, naročito kada su doze velike.
In lots of conditions, these metabolites are detectable in the body for for much longer in comparison to the drug by itself. The most common metabolites of Bensedin are nordiazepam, temazepam, and oxazepam.
Ovaj lek se primenjuje pod strogim nadzorom medicinskog osoblja, tako da nije verovatno da ćete primiti previsoku dozu. Ako imate bilo kakva pitanja, obratite se Vašem lekaru ili medicinskoj sestri.
Usled inhibicije CYP3A4 i/ili CYP2C19 metaboličkih puteva, povećana je koncentracija benzodiazepina u plazmi.
Anterogradna amnezija se može javiti i pri primeni terapijskih doza, iako se naročito uočava pri primeni velikih doza. Ovo stanje se najčešće javlja nekoliko sati nakon primene leka i zbog toga, da bi se smanjio rizik, pacijent treba da ima seven-8 sati neprekidnog sna nakon primene leka (videti odeljak 4.eight). Efekti amnezije mogu biti povezani sa neodgovarajućim ponašanjem.
Fluoksetin inhibira metabolizam diazepama preko CYP2C19 i ostalih metaboličkih puteva, što dovodi do povećanja koncentracije i smanjenja klirensa diazepama. Pojačano je dejstvo diazepama. Potreban je pojačan nadzor pri istovremenoj primeni.
This medicine has been prescribed for You simply. Tend not to go it on to Other people. It could hurt them, even if their signs of illness are the same as yours.
It's because getting excessive co-dydramol can result in severe damage to your liver And maybe Demise in critical circumstances. Take the container with you so that the medical professional is aware what continues to be taken.
Usporen metabolizam diazepama dovodi get more info do produženja poluvremena eliminacije i povećanja koncentracije diazepama u plazmi. Usporena je eliminacija N-demetil metabolita diazepama, što može značajno pojačati sedativni efekat. Povećan je rizik od inhibicije CNS, npr. sedacije.
Opioids ought to only be utilized by These they are prescribed for. Tend not to give your medication to everyone else. Having increased doses or more Repeated doses of opioid, may perhaps improve the risk of addiction. Overuse and misuse may lead to overdose and/or death.
variations in blood cells, which include very low quantity of cells which fight infection and of cells that are involved with blood clotting.
Due to these variables, Health care providers use benzodiazepines cautiously. Should your anxious procedure’s exercise drops as well lower, it might have perilous or perhaps deadly effects.
They’re Substantially safer than their predecessors. In advance of benzodiazepines, doctors primarily prescribed barbiturates for managing stress. But these medications came with significant threats bensedin 10 mg of aspect effects and problems.